Case studies

A scientist harvesting crystals for X-ray fragment screening campaign

Our collection of case studies offers an insightful look into the way we address scientific challenges and drive innovation to support our clients. Each case study exemplifies our methodical approach, highlighting how we collaborate closely with our partners to develop tailored solutions that meet their specific needs. By showcasing drug discovery and development projects and outcomes, these case studies demonstrate our commitment to excellence and our ability to navigate complex scientific landscapes to add value to our clients.

A projected molecular model in an office meeting room

ATR kinase inhibitor

Lead identification and optimisation using a combination of high-throughput screening and structure-based design

A scientist operates an HPLC machine, analyzing samples in a laboratory setting with precision and focus.

BTZ-043 human AME study

Handling the challenge of unstable hydride Meisenheimer complexes and other metabolites

A close-up on a structure of salt crystals

API polymorph selection

Achieving controlled production of polymorph B of an API, despite its inherent propensity to crystallise as polymorph A

Businessmen review procedures through documents containing company regulatory documents

European market authorisation

How we helped ensure compliance with EU GMP regulations through QA/QP oversight

A small vial with blue liquid in it is placed on a spectra paper showing chemical structure of a molecule

Codeine impurity identification

A complete [¹H], [¹³C] and [¹⁵N] assignment of an unknown codeine impurity

Two hands in gloves doing cream formulation

IVPT-guided formulation selection

Identifying a lead semi-solid formulation that resolves tolerability concerns without compromising dermal delivery performance

From oral to topical

Employing an integrated strategy to evaluate topical delivery potential of an oral small molecule

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