Compound screening

Identifying first hits is a crucial milestone in every drug discovery project. With over 25 years of experience, our custom high-throughput screening (HTS) services are designed to identify hit compounds tailored to your validated target, phenotype or mechanism. Access our library of over 3 million unique proprietary small molecule compounds for both full-deck and focused HTS screening options. Each compound is linked to our life science database, containing more than 500 million datasets for efficient hit selection. We also offer fragment-based screening using various biophysical methods and virtual screening services. You can be confident that the specific screening technology we use will be carefully chosen to best address your scientific question and target. 
Screening expert processing a stack of assay plates 

High-throughput screening (HTS)

In our highly automated laboratories, experienced scientists design and execute a wide range of miniaturised, cost-effective assays tailored to your therapeutic needs. Our state-of-the-art equipment enables both large-scale screening of our small-molecule library, containing up to 3 million compounds, and focused screening of smaller sub-libraries. We specialise in ultra-HTS campaigns using biochemical, biophysical, mass spectrometry, cellular and phenotypic high-content assays.

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A scientist harvesting crystals for X-ray fragment screening campaign

Fragment screening

Fragment screening is an efficient method for identifying new chemical matter quickly. We offer a broad range of biophysical and structural biology methods to identify initial binders from our proprietary library of 2,000 fragments, hand-selected by medicinal chemists. The 3D structure of fragment hits guides our expert medicinal and computational chemists in growing or linking approaches, often combined with HTS hits, to improve potency and selectivity.

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A projected molecular model in an office meeting room

Virtual screening

We offer diverse virtual screening options to find new chemical starting points or expand existing hits. Our platform, supported by our life science database with over 500 million data points, integrates state-of-the-art machine learning-based predictive tools for rapid hit prioritisation. We provide tailored solutions to meet the specific needs of your drug discovery programs, helping ensure effective and efficient results.

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Talk to us

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+49 731 9840 0 

Our locations

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Neu-Ulm (headquarters)

Wegenerstrasse 13

89231 Neu-Ulm

Germany

Berlin

Muellerstrasse 178

13353 Berlin

Germany

Sophia Antipolis

2400 route des Colles

06410 Biot

France

Grafing

Am Feld 32

85567 Grafing

Germany

Waltrop

Im Wirrigen 25

45731 Waltrop

Germany

For concerns about pharmaceuticals or adverse drug-related events, contact us at: complaints@nuvisan.com