Biochemical Assays

The foundation of any screening and hit characterization project is the development of carefully thought-out assays, including biochemical assays. With decades of industry experience, we are well-versed in designing, developing, running, and interpreting biochemical assays on a wide range of targets for high-throughput screening (HTS) campaigns, as well as for hit-to-lead and lead optimization.

As every screening project has unique hurdles and requires distinct strategies, we work closely with you to develop tailored high-quality biochemical assays meeting your specific project’s requirements.

We provide:

  • development of primary, orthogonal, counter-screen, cross-species, selectivity, and mode-of-action assays
  • close collaboration with our protein experts for designing and provisioning the best proteins in sufficient amounts for your project
  • employment of established assays to identify new hits in HTS and hit follow-up (hit-to-lead and lead optimization along the drug discovery pipeline
  • generation and interpretation of data for knowledge-based decision-making

More detailed information about our biochemical assay development: