Biomarkers

Biomarkers are measurable indicators of biological processes, conditions or diseases. They play a crucial role in medical research and patient care by providing valuable insights into disease mechanisms, diagnosis and treatment efficacy. Biomarkers can help identify diseases at an early stage, allowing for timely intervention. They enable tailored treatment plans (personalised medicine) based on individual biomarker profiles, improving patient outcomes. And they can help in the development of new drugs by identifying potential therapeutic targets and monitoring treatment responses. 

Every biomarker project is unique, and so is our approach. Our biomarker specialist team is dedicated to deliver meaningful data that drives impactful decisions by providing tailored and scientific consultation addressing each project’s specific needs. We offer many different assay types and analytical platforms, ranging from LC-MS/MS based assays to soluble markers analysed by ligand binding assays, to cell-based markers evaluated by flow cytometry or functional assays. For all biomarker applications, we always take the context-of-use into consideration to help you find the best strategy for the specific project needs and requirements.  
 
Scientist pushing virtual light bulb

Context-of-use

Defining the context of use helps ensuring that biomarker assays are developed, validated and applied in a manner that meets the specific needs and goals of the research or clinical application. It provides a framework for evaluating the assay’s performance and suitability, which can ultimately lead to more reliable and meaningful biomarker data. Based on the context of use, our experts not only suggest a suitable platform and assay type but also guide you through the fit-for-purpose validation setup. 

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Image showcasing antibody binding to human cell receptors 

Immunoassays (biomarkers)

By leveraging the specificity of antigen-antibody interactions, immunoassays enable precise detection of a wide array of biomolecules. Various platforms for ligand binding assays are available at Nuvisan, offering the flexibility to support biomarker projects individually. 

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Image showcasing a mass spectrometer

Chromatography and mass spectrometry (biomarkers)

Liquid chromatography-mass spectrometry (LC-MS) is a highly sensitive and specific analytical technique widely used for the analysis of a diverse range of biomarkers. Its ability to separate complex mixtures and identify compounds based on their mass-to-charge ratio makes it an invaluable tool.  

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Clinical laboratory

Located alongside our Clinical Pharmacology Unit (CPU), our clinical laboratory is committed to delivering highest-quality data and insights to not only support safety assessments but also pharmacodynamic biomarkers.  

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Polymerase chain reaction samples on dry ice

Isochronic library

Nuvisan’s own isochronic library was set up to support your biomarker stability assessment and help save you valuable time during assay validation.  

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Talk to us

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+49 731 9840 0 

Our locations

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Neu-Ulm (headquarters)

Wegenerstrasse 13

89231 Neu-Ulm

Germany

Berlin

Muellerstrasse 178

13353 Berlin

Germany

Sophia Antipolis

2400 route des Colles

06410 Biot

France

Grafing

Am Feld 32

85567 Grafing

Germany

Waltrop

Im Wirrigen 25

45731 Waltrop

Germany

For concerns about pharmaceuticals or adverse drug-related events, contact us at: complaints@nuvisan.com