The understanding of pharmacokinetics (PK) is a prerequisite for the success of a drug candidate. PK data in rodent and non-rodent species shed light on whether or not your compound has appropriate properties to qualify for preclinical pharmacology (efficacy) and safety studies. Our in vivo PK study portfolio offers a wide variety of study designs in various animal species. From assessment of basic PK properties for compound optimization and selection to more complex studies addressing special project needs, our experienced team will find the best approach for your research and drug development program.
By serial collection of microsamples, we can deliver a full PK profile in each individual animal with or without collection of excreta, even in mouse and rat.
Our analytical scientists and laboratory technicians have experience in quantifying analytes in a wide variety of matrices applying mass spectrometry.
Mouse, rat, dog, minipig, and genetically modified animals (mouse or rat)
Intravenous (bolus or infusion), oral, subcutaneous, intramuscular, intranasal, intratracheal, intraperitoneal, and topical
Blood, plasma, serum, urine, feces, bile, cerebrospinal fluid, broncho-alveolar lavage, and tissues
We understand the relevance and importance of fast turnaround times in drug discovery for compound optimization and offer a discovery PK business model enabling rapid data delivery within 5 days after dosing.
We deliver standardized reports using NUVISAN templates or customized reports according to your specific needs and requirements. Whether it is a format ready to be uploaded into your internal database, an abbreviated or even submission ready study report, you tell us how you would like to receive your DMPK data.