The goal of assay development is to establish a robust experimental setup that can be used to obtain reproducible results. For this purpose, the experimental environmental variables must be adjusted in the best possible way. Thus, the assay provides stable, empirical data sets that act as a basis for sound, scientific evaluations and enable trustworthy recommendations for the subsequent steps in the drug development process. In our laboratory, every assay undergoes a thorough quality management process in which the data sets are evaluated and validated by the scientific committee of our screening team. Only when all assay variables meet our high evaluation standard is the assay approved for productive use in screening or SAR studies.