We offer a range of xenograft and syngeneic models for multiple cancer indications, including solid and hematological tumor models, metastasis and colonization models, and immuno-oncology models. Our services include various study types, such as tolerability, pharmacokinetic and pharmacodynamic analyses, anti-tumor efficacy, imaging, and radiation. We have experience with small molecules and biologics and offer several analysis options, including tumor growth kinetics, biomarker analysis, and immune cell profiling. Our small animal facility is equipped with radiation and imaging capabilities, including bioluminescence, µCT, and US.
We have a knowledge base of > 200 oncology preclinical CDX models. A list of available models follows (further models might be available upon request):
Subcutaneous cell line derived xenograft (CDX) in mouse