Chemical Development

For your newest chemical innovation, we offer pivotal GLP and non-GLP screenings according to OECD guidelines. Our experts help to build a study design that yields reliable data and helps navigate your product through safety testing. As your partner, the success of your compound is our highest priority.

General Toxicology Studies

We offer systemic toxicity studies in compliance with REACH, OECD, and GLP. Our toxicology team acts as an extension of your development team and supports you with deep toxicology knowledge and years of experience conducting in vivo studies. We build trust through providing quality and efficiency. Study results can be closely monitored so that any amendments to the study protocol can be made in a timely fashion and in the best interests of our clients.

Our services include:

  • repeated-dose 28-day oral toxicity study in rodents
  • repeated-dose 90-day oral toxicity study in rodents
  • chronic toxicity studies in rodents (for 6 to 12 months)

Administration Routes

Substances can be administered

  • orally (po, gavage)
  • via diet or drinking water

The method of oral administration is dependent on the purpose of your study and the physical/chemical/toxicokinetic properties of the test material. Experimental protocols are carefully planned in collaboration with our experienced study directors, who are all veterinarians.

Specific Toxicology Testing

In addition to our standard end points, systemic toxicity studies can be complemented with a large range of GLP and non-GLP end points in collaboration with our internal experts and partners from our external network. Accordingly, we offer mechanistic toxicity studies that are closely monitored and guided by a toxicologist and a team of experts.


  • Clinical observations, including
    • functional observational battery
    • motor activity
    • ophthalmology
  • Clinical pathology (clinical chemistry, hemostasis, hematology, immunotoxicology)
  • Toxicokinetics
  • Toxicological pathology (necropsy and histopathology)
  • In vivo genotoxicity testing, to be integrated into general toxicity studies in rodents, such as:
    • mammalian erythrocyte micronucleus test
    • in vivo mammalian alkaline comet assay
    • mammalian erythrocyte pig-a gene mutation assay [coming soon]

For more information or study inquiries, please get in touch with our business development team and expert toxicologists.