Cardiovascular diseases

Our cardiovascular expertise 

At Nuvisan, we specialise in advancing drug discovery and development for cardiovascular diseases through comprehensive and integrated research services. Our capabilities span from target identification and validation to preclinical development and clinical translation. With state-of-the-art technologies and multidisciplinary expertise, we address critical challenges in cardiovascular drug development. 

Fibrillating heart in a medical imaging study

Capabilities overview 

Our cardiovascular research services offer end-to-end solutions, including: 

  • Target identification and validation: employing functional genomics (CRISPR/Cas9), bioinformatics and omics analyses to identify and validate novel targets
  • In vitro assay development: tailored cell models, including human iPSC-derived cardiac cells for mechanistic and pathway analyses.
Stylised image of DNA editing using CRISPR 

CV technology platform 

Our technology platforms support research in the fields of: 

  • Hereditary cardiac disease 
  • Arrhythmias and heart failure 
  • Cardiac fibrosis.

 

We support your cardiovascular projects with: 

Human iPSC-derived cell models 

  • Ventricular and atrial cardiomyocytes 
  • Cardiac fibroblasts
  • Cardiac endothelial cells 
  • 3D engineered cardiac organoids (ECOs).

 

Imaging and analysis 

  • Multi-electrode array (MEA) for electrophysiological studies 
  • Impedance-based endothelial/epithelial barrier assays 
  • Non-invasive imaging platforms for functional assessments.

 

High-throughput screening

  • Screening of small and large molecule libraries, including fragment-based and virtual approaches 
  • High-content imaging with advanced imaging systems for live-cell analysis and phenotypic screening.

 

Metabolic profiling: Seahorse analyser for mitochondrial and cellular energetics.

 

Related topics & resources

The “strings” of the heart that contract and relax with every beat.

Human stem cell platform

We are constantly expanding our hiPSC-derived cell portfolio in the cardiology and neurology indication spaces.

learn more about Human stem cell platform
MACS Quant Flow Cytometer in action

Immunology platform

Explore how our scientists support your research projects with our immunology platform.

learn more about Immunology platform
Translucent human body illustration showcasing key organs involved in metabolic processes.

Neuroscience

Discover our service portfolio in the neuroscience field.

learn more about Neuroscience

Contact us

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Email us

hello@nuvisan.com

Talk to us

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+49 731 9840 0 

Our locations

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Neu-Ulm (headquarters)

Wegenerstrasse 13

89231 Neu-Ulm

Germany

Berlin

Muellerstrasse 178

13353 Berlin

Germany

Sophia Antipolis

2400 route des Colles

06410 Biot

France

Grafing

Am Feld 32

85567 Grafing

Germany

Waltrop

Im Wirrigen 25

45731 Waltrop

Germany

For concerns about pharmaceuticals or adverse drug-related events, contact us at: complaints@nuvisan.com