Biomarker discovery 

Advance your project with our biomarker discovery expertise  

Our dedicated team works to identify and validate pharmacodynamic, target engagement and selection biomarkers using preclinical in vitro and in vivo models, tailored to your needs. We profile the clinical indication space with our tissue biobank to pinpoint patient populations relevant to your research. By leveraging biomarkers, we provide valuable insights into the pharmacokinetic/ pharmacodynamic (PK/PD) relationship of novel drug candidates. Additionally, we analyse biomarkers from your clinical trial samples to help ensure seamless translation of preclinical findings to clinical applications.  

Whole slide scanning of IHC staining

Precision medicine enabled

We offer integrated biomarker services, covering the entire drug discovery value chain—from preclinical biomarker discovery and validation to robust assay development, indication space population profiling and biomarker analysis of clinical samples. Our experienced biomarker scientists, with a decade-long background in the pharma industry, bring extensive knowledge across various therapeutic areas and modalities. We have a proven track record of successfully translating your drug discovery programs into clinical applications, ensuring your research progresses smoothly and effectively.

identification and validation of biomarkers

Biomarker technology platform  

Our biomarker technology platform integrates advanced global and targeted profiling techniques to deliver comprehensive and precise data tailored to your research and diagnostic needs. By utilising state-of-the-art methods, we help ensure reliable and insightful biomarker discovery and validation.

 

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In vivo biomarker services

At Nuvisan, we understand that in vivo pharmacodynamic (PD) biomarker and pharmacokinetic/pharmacodynamic (PK/PD) studies are crucial for your research. These studies help determine the optimal dose, administration route and dosing schedule of a drug by analysing the relationship between drug exposure and its pharmacodynamic effects, enabling the most effective and tailored outcomes for your projects.

 

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Clinical translation of biomarkers

Our team provides biomarker indication profiling using immunohistochemistry (IHC) based on comprehensive clinical sample collections, helping ensure precise and reliable results. We conduct clinical sample biomarker analysis in strict accordance with good clinical practice (GCP), prioritising the highest standards for your research needs.

 

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Related topics & resources

Our next-generation sequencing (NGS) platform services

Biomarkers technology platforms

Our hypothesis-free global and mode-of-action hypothesis-driven approaches are tailored to your research needs.

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Multicolor immunofluorescence (mIF) for immune cell infiltration

In vivo biomarker services

Discover the power of in vivo biomarker analysis to bridge the gap between preclinical research and clinical success. 

Learn More about In vivo biomarker services
Biomarker scientists performing immunohistochemistry

Clinical translation of biomarkers

Our teams offer biomarker validation to confirm clinical relevance of your biomarkers across both preclinical and patient samples.

Learn More about Clinical translation of biomarkers

Contact us

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Email us

hello@nuvisan.com

Talk to us

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+49 731 9840 0 

Our locations

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Neu-Ulm (headquarters)

Wegenerstrasse 13

89231 Neu-Ulm

Germany

Berlin

Muellerstrasse 178

13353 Berlin

Germany

Sophia Antipolis

2400 route des Colles

06410 Biot

France

Grafing

Am Feld 32

85567 Grafing

Germany

Waltrop

Im Wirrigen 25

45731 Waltrop

Germany

For concerns about pharmaceuticals or adverse drug-related events, contact us at: complaints@nuvisan.com