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Excellent Center for In vitro and In vivo DMPK, Isotope Chemistry and Discovery & Regulatory Bioanalysis.
Including a state oft the art Animal Housing, dedicated Equipment for radioactive Synthesis and sufficient Technologies for Bioanalysis of Small Molecules for Discovery and Development.
Infrastructure
Headcount: 53 (42% university graduates)
Lab Capacity: 1.200 m² Space
Animal Housing Capacity: 1.000 m²
Bioanalytical Capacity: 220 m²
Inspections & Authorizations
GLP certified (1990)
AAALAC Accreditation
License to work with radioactivity (14C, 3H) and genetically modified organisms (S1)
History
Established in 1965 and hold by Merck KGaA for Discovery and Development of DMPK
Acquisition from Merck KGaA in 2016
Today Grafing supports non-clinical in vitro and in vivo DMPK with Merck KGaA as partner
Working Fields & Specialties
In vitro & In vivo DMPK
Bioanalysis with respect to discovery and GLP bioanalysis with fast turnaround times
Metabolite Profiling and Identification
Radiosynthesis/Isotope Labelling & QWBA
Mass Spectometry with license to handle radioactivity: human mass balance studies can be supported
