In vivo toxicology testing
In vivo toxicology testing is a critical step in characterising the safety of your potential products, particularly for long-term use or exposure to vulnerable populations. Our non-GLP studies are ideal for early-stage safety assessments and screening, while GLP-compliant studies ensure that your new drug or chemical meets stringent regulatory requirements. By testing in both rodent and non-rodent species, you gain the necessary data to move forward with confidence.
Non-GLP studies (screening studies):
- Acute toxicity: Assess the potential lethal or harmful effects of a single exposure to your test item in rodents and non-rodent species. Different administration routes, ranging from oral to dermal exposure, can be conducted to evaluate the immediate impact of your test item.
- Subchronic toxicity: Evaluate the effects of repeated exposure over a short-term period (2 to 4 weeks) to understand potential risks from prolonged use.
GLP-compliant studies (regulatory studies):
- Chronic toxicity studies: Long-term studies (13 weeks or more) to evaluate the potential adverse effects of chronic exposure to your test item
- Carcinogenicity testing: In-depth studies to assess the potential cancer-causing effects of long-term exposure, using rodent models that can provide reliable, regulatory-compliant data
- Reproductive and developmental toxicity: Studies designed to evaluate the impact of your test item on fertility, reproductive health and developmental processes in rodent and non-rodent species.
- Immunotoxicity testing: Evaluate the potential effects of your test item on the immune system, identifying any risks that could impact immune function or lead to adverse immune responses.
These essential studies help ensure the safety and efficacy of your product, providing valuable data for regulatory submissions and guiding the development process.
