Chromatography and mass spectrometry

Biomarker analysis using LC-MS offers several advantages  

• High sensitivity and specificity: LC-MS can detect and quantify biomarkers at very low concentrations and it also provides high specificity due to its ability to distinguish between compounds with similar masses.
• Wide dynamic range: This technique can analyse a broad range of biomarker concentrations, from very low to very high levels.
• Versatility: LC-MS can be used for a variety of biomolecules, including proteins, peptides, metabolites and small molecules.
• Quantitative accuracy: It provides precise quantitative data, which is crucial for biomarker validation and clinical applications.
• Multiplexing capability: LC-MS can analyse multiple biomarkers simultaneously in a single run, increasing throughput and efficiency.