Preformulation

Solubility and compatibility analysis

Nuvisan provides comprehensive drug substance (DS) solubility and compatibility profiling using advanced techniques like ultra-performance liquid chromatography (UPLC) with a diode array detector (DAD). We analyse both single excipients and mixtures, enabling rational excipient selection and formulation design. This data helps optimise API solubility, stability and skin delivery while considering tolerance and sensory aspects.

Our efficient R&D approach generates solubility and compatibility profiles with key ingredients, facilitating rapid formulation development. These well-defined profiles allow our experts to quickly select the most appropriate formulation technologies and create customised compositions tailored to your molecule's specific needs.

Whether you require end-to-end development for a commercial formula or exploratory formulations, Nuvisan adapts formulations to fit your molecule's physicochemical properties, ensuring swift project advancement. Our continuously updated formulation science and technology library supports our innovative approach, making Nuvisan a leader in efficient and effective topical and oral liquid product development.

Preliminary degradation tests

Forced degradation screening helps identify ideal formulation conditions, such as preferred pH, and indicates the need for stabilisers like antioxidants. This critical process is carried out in close collaboration between our chemistry and analytics teams.

Nuvisan's complementary, high-tech and express approach involves cross-functional teams of formulators, chemists and analysts, shortening development timelines and accelerating your projects to proof-of-concept studies.