Topical liquid and semi-solids formulations
With centuries of combined experience in topical formulation development, Nuvisan offers a diverse toolbox of solutions and innovative approaches to meet the specific needs of any topical product. Our team is committed to ensuring that your project is delivered on schedule with excellent quality, from early-stage de-risking to late-stage troubleshooting.
We operate a 450 m² laboratory dedicated to topical drug formulation, divided into seven secure, isolated labs, including four equipped for handling highly potent molecules.
Guided by the target product profile (TPP) and preformulation data, we conduct formulation screening, stability evaluations (chemical, physical and microbiological), and in vitro skin permeability studies to optimise formulations. Microstructure and sensory properties are also characterised. Preclinical in vitro toxicology testing is used to assess local tolerance as well while in vitro and in vivo models permit evaluation of pharmacologic effects in inflammatory and non-inflammatory skin diseases (e.g. imiquimod-induced psoriasis in mice). This comprehensive approach supports the creation of formulations that are adapted to the specific needs of the compound, indication and patient.
Nuvisan’s integrated approach guides the development of effective, well-tolerated and cosmetically elegant formulations, offering flexibility for both start-ups and big pharma.
