Stable Isotope Synthesis (2H, 13C, 15N)

Stable isotope labeled compounds are used as internal standards in analytical chemistry to provide control for extraction, ionization, and injection variability and are thus essential components for robust mass spectrometry-based bioanalysis. Moreover stable label compounds have a use in mechanistic studies.

For its use as effective internal standard, the stable isotope labeled compound must show similar properties ideally resulting in identical chromatographic retention time, extraction recovery, and ionization compared to the analyte of interest, while mass spectrometric responses must be sufficiently resolved to enable identification of both substances.

Our team is skilled to cover a wide range of chemistry with vast experience in different transformations and chemical reactions. We have successfully delivered reams of stable isotope labeled molecules from a diverse spectrum of compound classes, including small molecules, peptides, carbohydrates, lipids, and many more.