Method List

BIOANALYTICAL METHODS / ANALYTE(S)

LLOQ

Units

Matrix

Methodology

Acetaminophen

0.25

μg/mL

Plasma

LC/MS/MS

Acetaminophen/ Tramadol

100 / 5

ng/ml

Plasma

LC/MS/MS

Albuterol

0.5

ng/mL

Plasma

GC/MS

Aldosterone

25

pg/mL

Serum

ELISA

Alendronate

1 / 0.5

ng/ml

Urine/Plasma

LC/MS/MS

Alkaline Hematin
(Menstrual Blood)

3

ml

Feminine Hygeine Prod.

Colorimetric

Allopurinol / Oxypurinol

50 /100

ng/mL

Plasma

LC/MS/MS

Alprazolam

50

pg/mL

Plasma

GC/MS

Alprazolam

0.5

ng/mL

Plasma

LC/MS/MS

Aluminum

5/2

ng/mL

Plasma/Urine

ICP/MS

Amikacin

0.15

ug/ml

Serum

LC/MS/MS

5-Aminosalicylic acid/
N-acetyl-5-aminosalicylic acid

10/20

ng/mL

Plasma

LC/MS/MS

Amiodarone / Desethylamiodarone

10 / 10

ng/mL

Plasma

LC/MS/MS

Amitriptyline

200

pg/ml

Plasma

LC/MS/MS

Amlodipine

50

pg/mL

Plasma

LC/MS/MS

Amphetamine

100

pg/mL

Plasma/Serum

GC/MS

Articaine

10

ng/mL

Plasma/Urine

GC/MS

Articainic Acid

20

ng/mL

Plasma/Urine

GC/MS

Atenolol

10

ng/mL

Plasma

LC/MS/MS

Atenolol

250

ng/mL

Urine

LC/MS/MS

Atorvastatin/O-hydroxy/
P-hydroxy atorvastatin

200/100/20

pg/ml

Plasma

LC/MS/MS

Atropine

50

pg/mL

Plasma

GC/MS

Atomoxetine

10

ng/ml

Plasma

LC/MS/MS

Azathioprine/
6-Mercaptopurine

1/1

ng/mL

Plasma

LC/MS/MS

Azithromycin

2

ng/mL

Plasma

LC/MS/MS

Benazepril /
Benazeprilat

5 / 10

ng/mL

Plasma

LC/MS/MS

Benidipine

50

pg/mL

Plasma

GC/MS

Betahistine

5

pg/mL

Plasma

LC/MS/MS

Betamethasone

50

pg/mL

Plasma

GC/MS

Bicalutamide

2.5

ng/mL

Plasma

LC/MS/MS

Biperiden

250

pg/mL

Plasma

GC/MS

Bismuth

0.5

ng/mL

Plasma

ICP-MS

Bisoprolol

0.2

ng/ml

Plasma

LC/MS/MS

Boswellic Acid

50

ng/mL

Plasma

GC/MS

Bromine

0.5

μg/mL

Plasma

ICP/MS

Bromocriptine

2.5

pg/mL

Plasma

LC/MS/MS

Brompheniramine

0.5

ng/mL

Plasma

LC/MS/MS

Budesonide/16-OH Budesonide/16-OH Prednisolone

0.1/0.1/0.5

ng/ml

Plasma

LC/MS/MS

Buprenorphine

25

pg/mL

Plasma

GC/MS

Buprenorphine / Norbuprenorphine

5 / 5

pg/ml

Plasma

LC/MS/MS

Buspirone / 1-PP

100

pg/mL

Plasma

LC/MS/MS

Butorphanol

20

pg/mL

Plasma

LC/MS/MS

Canrenone

2

ng/mL

Plasma

LC/MS/MS

Canrenone

20

ng/mL

Urine

LC/MS/MS

Capric Acid

100

ng/ml

Plasma

LC/MS/MS

Cetirizine

2

ng/ml

Plasma

LC/MS/MS

Chlorhexidine

25

ng/ml

Saliva

LC/MS/MS

Chlormadinone Acetate

50

pg/mL

Plasma

GC/MS

Citalopram

100

pg/mL

Plasma

LC/MS/MS

Citric Acid

50

ng/ml

Urine

LC/MS/MS

Clarithromycin

10

ng/mL

Plasma

LC/MS/MS

Clemastine

100

pg/mL

Plasma

GC/MS

Clenbuterol

0.2

ng/mL

Plasma / Urine

GC/MS

Clindamycin

100

ng/mL

Plasma

LC/MS/MS

Clonazepam

100

pg/ml

Plasma

LC/MS/MS

Clonidine

25

pg/mL

Plasma

GC/MS

Clozapine

0.1

ng/mL

Plasma

LC/MS/MS

Codeine

1

ng/mL

Plasma

LC/MS/MS

Cortisol

1

Ng/ml

Plasma

LC/MS/MS

Cyclobenzaprine

0.1

ng/mL

Plasma

LC/MS/MS

Cyclosporin

10

ng/ml

Whole Blood

LC/MS/MS

Cyproterone Acetate

25

pg/mL

Plasma/Serum

GC/MS

Desmopressin

2.5

pg/ml

Plasma

LC/MS/MS

Desogestrel
(3-keto-desogestrel)

25

pg/mL

Plasma

GC/MS

Desogestrel
(3-keto-desogestrel) /Ethinylestradiol

25/2.5

pg/ml

Plasma

GC/MS

Dexamethasone

0.25

ng/mL

Plasma

LC/MS/MS

Diclofenac

5

ng/ml

Plasma

LC/MS/MS

Dienogest

0.5

ng/ml

Plasma

LC/MS/MS

Digoxin

1

ng/mL

Urine

LC/MS/MS

Digoxin

1

ng/ml

Plasma

LC/MS/MS

Diltiazem /
Desmethyldiltiazem / Desacetyldiltiazem

4/2/1

ng/mL

Plasma

LC/MS/MS

Diphenydramine

1

ng/mL

Plasma

LC/MS/MS

Disulfiram (as Methyl Diethydithiocarbamate)

1.0

ng/mL

Plasma

GC/MS

Docetaxel

2.5

ng/ml

Plasma

LC/MS/MS

Doxorubicin

1.5

ng/ml

Urine

LC/MS/MS

Doxorubicin /
Doxorubicinol

0.5 / 0.5

ng/ml

Plasma

LC/MS/MS

Dronabinol /
11-OH-Dronabinol

200/200

pg/ml

Plasma

LC/MS/MS

Drospirenone

100

pg/ml

Plasma

LC/MS/MS

Dydrogesterone

50

pg/mL

Plasma

GC/MS

Enalapril & Enalaprilat

250

pg/mL

Plasma

LC/MS/MS

Eprosartan

1

ng/ml

Plasma

LC/MS/MS

Ergotamine

25

pg/mL

Plasma

LC/MS/MS

Estradiol / Estrone

5 / 5

pg/mL

Plasma/Serum

GC/MS

Estradiol / Estrone

2.5 / 5

pg/mL

Plasma/Serum

GC/MS

Estradiol / Estrone

1 / 2

pg/mL

Serum

GC/MS

Estradiol / Estrone

50 / 100

pg/mL

Rat Plasma/Serum

GC/MS

Estriol

10.0

pg/mL

Plasma/Serum

GC/MS

Free Estrone / Equilin /
Estradiol / Delta-8,9-Dehydroestrone

5/5/2.5/2.5

pg/mL

Plasma

GC/MS

Total Estrone / Equilin /
Estradiol / Delta-8,9-Dehydroestrone

50/50/10/10

pg/mL

Plasma

GC/MS

Estrone Sulfate

50

pg/ml

Plasma

LC/MS/MS

Estrone Sulfate

50

pg/mL

Plasma

GC/MS

EthinylEstradiol

1

pg/ml

Plasma

GC/MS

Ethinylestradiol

2.5

pg/mL

Plasma

GC/MS

Ethinylestradiol /
Norethindrone

2.5 / 25

pg/mL

Plasma

GC/MS

Ethinylestradiol /
Norgestrel (levonorgestrel)

10 / 50

pg/mL

Serum

GC/MS

Etoposide

0.5

ng/mL

Plasma

LC/MS/MS

Exemestane

50

pg/ml

Plasma

LC/MS/MS

Famotidine

2

ng/mL

Plasma

LC/MS/MS

Felodipine

50

pg/mL

Plasma

GC/MS

Felodipine

25

ng/ml

Plasma

LC/MS/MS

Fenofibric Acid

10

ng/mL

Plasma

LC/MS/MS

Fentanyl

25

pg/mL

Plasma

LC/MS/MS

Finasteride

0.5

ng/ml

Plasma

LC/MS/MS

Flavoxate /
MFCA metabolite

0.1/50

ng/mL

Plasma

LC/MS/MS/HPLC UV

Fludrocortisone

25

pg/mL

Plasma

GC/MS

Flunisolide

50

pg/mL

Plasma

GC/MS

Fluspirilene

25

pg/mL

Plasma

GC/MS

Flutamide /
Hydroxyflutamide

20/2

pg/mL

Plasma

GC/MS

Fluvoxamine

200

pg/mL

Plasma

LC/MS/MS

Fosinoprilat

5

ng/mL

Plasma

LC/MS/MS

Furnidipine

25

pg/mL

Plasma

GC/MS

Furosemide

50

ng/ml

Plasma

LC/MS/MS

Gabapentin

50

ng/mL

Plasma

LC/MS

Gadolinium

1

μg/mL

Serum/Urine

ICP/MS

Gliclazide

5

ng/mL

Plasma

LC/MS/MS

Glimepiride

1

ng/mL

Serum

LC/MS/MS

Goserelin

0.2

ng/ml

Plasma

LC/MS/MS

Guaifenesin

2.5

ng/mL

Plasma

LC/MS/MS

Haloperidol

25

pg/mL

Plasma

LC/MS/MS

Homocysteine

5

μg/mL

Plasma

LC/MS/MS

Hydrocodone

0.25

ng/mL

Plasma

LC/MS/MS

Hydromorphone

20.0

pg/mL

Plasma

LC/MS/MS

Hydroxymephenytoin,
(R)--4-/ Hydroxymephenytoin, (S)-4-

10

ng/mL

Plasma/Saliva

LC/MS/MS

Hydroxymephenytoin,
(R)--4-/ Hydroxymephenytoin, (S)-4-

0.1

μg/mL

Urine

LC/MS/MS

Hydroxymidazolam, a / Hydroxymidazolam, 4-

2 / 2

ng/mL

Plasma

LC/MS/MS

2-Hydroxypropyl-beta-cyclodextrin

0.1

μg/mL

Plasma

LC/MS

Hyoscyamine

50

pg/mL

Plasma

GC/MS

Ibuprofen

0.25

μg/mL

Plasma

LC/MS/MS

Ibuprofen R- / S-

0.25

μg/mL

Plasma

LC/MS/MS

Iloprost

10

pg/ml

Plasma

LC/MS/MS

Imipramine /
Desipramine

0.10

ng/mL

Plasma

LC/MS/MS

Indapamide

0.5

ng/mL

Plasma

LC/MS/MS

Indomethacin

20

ng/mL

Plasma

LC/MS/MS

Interferon alpha

10

pg/mL

Serum

ELISA

Iodine

0.5/5

μg/mL

Whole Blood/Urine

ICP/MS

Irbesartan

5

ng/mL

Plasma

LC/MS/MS

Isosorbide Dinitrate

0.1

ng/mL

Plasma

GC/MS

Isosorbide-2-mononitrate

0.25

ng/mL

Plasma

GC/MS

Isosorbide-5-mononitrate

0.25

ng/mL

Plasma

GC/MS

Isotretinoin /
4-Oxo-Isotretinoin

10

ng/mL

Plasma

LC/MS/MS

Isradapine

100

pg/mL

Plasma

LC/MS/MS

Ketoprofen

1

ng/mL

Plasma

LC/MS/MS

Ketoprofen

50

ng/mL

Urine

GC/MS

Ketotifen

25

pg/mL

Plasma

GC/MS

Lacidipine

20

pg/mL

Plasma

LC/MS/MS

Lamotrigine

10

ng/mL

Plasma

LC/MS/MS

Lercanidipine R- & S-

20

pg/ml

Plasma

LC/MS/MS

Letrozole

10

ng/ml

Plasma

LC/MS/MS

Leuprolide

0.04

ng/mL

Plasma

EIA

Levofloxacin

0.2

μg/mL

Plasma

LC/MS/MS

Levonorgestrel

10

pg/mL

Plasma/Serum

GC/MS

Lisinopril

1

ng/ml

Plasma

LC/MS/MS

Lisuride

10

pg/ml

Plasma

LC/MS/MS

Lithium

25

ng/mL

Serum

ICP/MS

Loperamide

125

pg/mL

Plasma

GC/MS

Loratadine / Descarboethoxyloratadine

100/50

pg/mL

Plasma

GC/MS

Lorazepam

1.0

ng/mL

Plasma

LC/MS/MS

Lynestrenol

0.1

ng/mL

Plasma

GC/MS

Medrogestone

50

pg/mL

Plasma

GC/MS

Medroxyprogesterone
Acetate

0.1

ng/mL

Plasma/Serum

GC/MS

Megesterol Acetate

100

pg/mL

Plasma

GC/MS

Melatonin

5

pg/mL

Plasma

LC/MS/MS

Meloxicam

10

ng/mL

Plasma

LC/MS/MS

Melperone

0.25

ng/mL

Plasma

GC/MS

Memantine

100

pg/mL

Plasma

GC/MS

Mephenytoin (R,S)

Phenotyping

 

Urine

GC/MS

R-Mephenytoin /
S-Mephenytoin

10

ng/mL

Plasma/Saliva

LC/MS/MS

R-4-Hydroxymephenytoin /
S-4-Hydroxymephenytoin

10

ng/mL

Plasma/Saliva

LC/MS/MS

R-4-Hydroxymephenytoin /
S-4-Hydroxymephenytoin

0.1

μg/mL

Urine

LC/MS/MS

R-Mephenytoin /
S-Mephenytoin

0.1

μg/mL

Urine

LC/MS/MS

Metformin

10

ng/mL

Plasma

LC/MS/MS

Methamphetamine

100

pg/mL

Plasma/Serum

GC/MS

Methoxyestradiol/
Methoxyestrone

5

pg/mL

Plasma

GC/MS

Methylnicotinamide

10

ng/ml

Plasma

LC/MS/MS

Methylphenidate

100

pg/ml

Plasma

LC/MS/MS

Methylprednisolone

0.5

ng/mL

Plasma

LC/MS/MS

Methyltestosterone

50

pg/mL

Plasma

GC/MS

Metoprolol

1.00

ng/mL

Plasma

LC/MS/MS

Midazolam

0.5

ng/mL

Plasma

GC/MS-LC/MS

Mirtazapine

0.5

ng/mL

Plasma

GC/MS

Misoprostol Acid

10

pg/ml

Serum

LC/MS/MS

Moexipril

1

ng/ml

Plasma

LC/MS/MS

Molindone

250

pg/ml

Plasma

LC/MS/MS

Morphine / Morphine-3-glucuronide / Morpine-6-glucuronide

0.5/5/2

ng/mL

Plasma

LC/MS/MS

Moxonidine

0.05/1

ng/mL

Plasma/Urine

GC/MS

Mycophenolic Acid / Mycophenolic Acid Glucuronide

0.1/0.5

ug/ml

Dog Plasma

LC/MS/MS

Niacin (Nicotinic Acid) / Nicotinuric acid

25

ng/mL

Plasma

LC/MS/MS

Nicardipine

25

pg/mL

Plasma

GC/MS

Nicorandil

1

ng/mL

Plasma

GC/MS

Nicotine / Cotinine

0.5/2.5

ng/mL

Plasma

GC/MS

Nilvadipine

50

pg/mL

Plasma

GC/MS

R-Nirvanol / S-Nirvanol

20

ng/mL

Plasma/Saliva

LC/MS/MS

R-Nirvanol / S-Nirvanol

0.25

μg/mL

Urine

LC/MS/MS

Nitisonon

1

ng/ml

Plasma

LC/MS/MS

Nitrendipine

50

pg/mL

Plasma

GC/MS

Nitroglycerin / 1,2 GDN /
1,3 GDN

5.20.10

pg/mL

Plasma

GC/MS

Norethindrone

25

pg/mL

Plasma

GC/MS

Norgestimate / 17-Desacetylnorgestimate

100

pg/mL

Plasma

LC/MS/MS

Norgestrel

0.1

ng/mL

Plasma

GC/MS

Octreotide

25

pg/mL

Plasma

LC/MS/MS

Ondansetron

0.5

ng/mL

Plasma

LC/MS/MS

Oxandrolone

0.25

ng/mL

Plasma

LC/MS/MS

Oxeladin

1

ng/mL

Plasma

GC/MS

Oxybutynin / N-Desethyloxybutynin

0.1/0.25

ng/mL

Plasma/Serum

LC/MS

Oxycodone and
Noroxycodcone

0.25

ng/mL

Plasma

LC/MS/MS

Pantoprazole

10

ng/mL

Plasma

LC/MS/MS

Paroxetine

100

pg/mL

Plasma

LC/MS/MS

Pentaerythrityl
Mononitrate &
Dinitrate

50

pg/mL

Plasma

GC/MS

Pentoxyverine

1

ng/mL

Plasma

GC/MS

Permetrexed

10

ng/ml

Plasma

LC/MS/MS

PGF2
(9-alpha, 11-beta PGF2)

25

pg/mL

Plasma

LC/MS/MS

Platinum

2.5

ng/mL

Plasma

ICP/MS

Potassium

1

mM

Urine

Ion Selective Electrode

Pravastatin

0.5

ng/mL

Plasma

LC/MS/MS

Primidone

25

ng/ml

Plasma

LC/MS/MS

Progesterone

100

pg/mL

Plasma

LC/MS/MS

Promethazine

200

pg/mL

Plasma

LC/MS/MS

Propafenone and
N-despropyl- & 5-Hydroxypropafenone

250

pg/mL

Plasma

LC/MS/MS

Propoxyphene /
Acetaminophen

1 / 50

ng/ml

Plasma

LC/MS/MS

Propoxyphene / Norpropoxyphene

1

ng/ml

Plasma

LC/MS/MS

PSA

360

pg/ml

Serum

EIA

Pseudoephedrine/
Ibuprofen

2/200

ng/mL

Plasma

LC/MS/MS

Quercetin

0.25

μg/mL

Plasma

LC/MS/MS

Repaglinide

200

pg/ml

Serum

LC/MS/MS

Ribavirin

25

ng/mL

Plasma

LC/MS/MS

Risedronic Acid

0.1 / 0.2

ng/ml

Plasma / Urine

LC/MS/MS

Risperidone

0.1

ng/mL

Plasma

LC/MS/MS

Rivastigmine

0.1

ng/ml

Plasma

LC/MS/MS

Ropinirole

20

pg/mL

Plasma

LC/MS/MS

Rosuvastatin

0.25

ng/ml

Plasma

LC/MS/MS

Scopolamine Free

25

pg/mL

Plasma

GC/MS

Scopolamine Free

100

pg/mL

Urine

GC/MS

Selegiline

50

pg/mL

Plasma/Serum

GC/MS

Desmethylselegiline / Methamphetamine / Amphetamine

100

pg/mL

Plasma/Serum

GC/MS

Sertraline

250

pg/mL

Plasma

GC/MS

SHBG

10

nmol/L

Plasma/Serum

ELISA

Simvastatin /
Simvastatin
Hydroxyacid

0.5/0.5

ng/mL

Plasma

LC/MS/MS

Sitagliptin

100

pg/ml

Plasma

LC/MS/MS

Sirolimus

1

Ng/ml

Blood

LC/MS/MS

Sparteine / 2-DHSP /
5-DHSP

0.5

nmol/L

Urine

GC/MS

Spironolactone

2

ng/mL

Plasma

LC/MS/MS

Strontium

100

ng/ml

Plasma

ICP/MS

Sumatriptan

0.5

ng/mL

Plasma

LC/MS/MS

Tacrolimus

0.5

ng/ml

Blood

LC/MS/MS

Temazepam

25

ng/mL

Plasma

LC/MS/MS

Terbinafine / N-desmethylterbinafine

40

Pg/ml

Plasma

LC/MS/MS

Terfenadine

0.1

ng/mL

Plasma

GC/MS

Testosterone / 5-α-Dihydrotestosterone

50

pg/mL

Plasma

GC/MS

Testosterone

100

pg/ml

Plasma

LC/MS/MS

Tizanidine

100

pg/mL

Plasma

LC/MS/MS

Tolperisone

500

pg/ml

Plasma

LC/MS/MS

Tolterodine /
5-hydroxymethyl
tolterodine

100

pg/mL

Plasma

LC/MS/MS

Topiramate

10

ng/mL

Plasma

LC/MS/MS

Tramadol/Acetaminophen

5/100

ng/nl

Plasma

LC/MS/MS

Tranexamic Acid

50

ng/mL

Plasma

GC/MS

Triamterene

2

ng/ml

Plasma

LC/MS/MS

Triazolam

50

pg/mL

Plasma

GC/MS

Venlafaxine / O-desmethylvenlafaxine

2.5

ng/ml

Plasma

LC/MS/MS

Vinorelbine

1

ng/mL

Blood

LC/MS/MS

Voriconazole

25

ng/mL

Plasma (Dog)

LC/MS/MS

Zolpidem

1

ng/mL

Plasma

LC/MS/MS

 

 

 

 

 

 

 

 

 

 

FOR REDEVELOPMENT / REVALIDATION BY LC-MS/MS

BIOANALYTICAL METHODS ANALYTE(S)

LLOQ

Units

Matrix

Methodology

Acebutalol / Diacetolol

5

ng/mL

Plasma

HPLC/UV

Acetaminophen

0.1

μg/mL

Plasma/Urine

HPLC/UV

N-Acetylcysteine

100

ng/mL

Plasma

HPLC/UV

Acetylsalicylic acid/Salicylic acid

25/50

ng/mL

Plasma

HPLC/UV

Acyclovir

20

ng/mL

Plasma

HPLC/FL

Acyclovir

1

μg/mL

Urine

HPLC/FL

Alfuzosin

250

pg/ml

Plasma

HPLC/Fl

Ambroxol

1

ng/mL

Plasma

HPLC/UV

Amiloride

1

ng/mL

Plasma

HPLC/FL

Aminoguanidine

50

ng/mL

Plasma

HPLC/EC

5-Aminosalicylic acid

2

μg/mL

Urine

HPLC/FL

5-Aminosalicylic acid

1

ng on col

Feces

HPLC/FL

Amitriptyline / Nortriptyline/ Amitriptylline-N-oxide

0.5/0.5/50

ng/mL

Plasma

HPLC/UV

Amoxicillin

0.25

μg/mL

Plasma

HPLC/UV

Ampicillin

0.25

μg/mL

Plasma

HPLC/UV

Anipamil

5

ng/mL

Plasma

HPLC/FL

Antipyrine

0.025

μg/mL

Plasma

HPLC/UV

Antipyrine & metabolites

2.5

μg/mL

Urine

HPLC/UV

Astemizole / Desmethylastemizole

250/150

pg/mL

Plasma

HPLC/EC

Atenolol R- / S-

20

ng/mL

Plasma

HPLC/FL

Benserazide

10

ng/mL

Plasma

HPLC/EC

Betaxolol

2

ng/ml

Plasma

HPLC/Fl

Bisoprolol / Bisoprolol
Fumerate

2/1

ng/mL

Plasma

HPLC/FL

Bromazepam

1

ng/mL

Plasma

HPLC/UV

Bromhexine / Ambroxol

1

ng/mL

Plasma

HPLC/UV

Bupropion

2.5

ng/mL

Plasma

HPLC/UV

Butalbital

0.1

μg/mL

Plasma

HPLC/UV

Caffeine

0.05

μg/mL

Plasma

HPLC/UV

Captopril

25

ng/mL

Plasma

HPLC/EC

Carabastine

5

ng/mL

Plasma

HPLC/UV

Carbamazepine

0.05

μg/mL

Plasma

HPLC/UV

Carbidopa / Levodopa / 3-O-Methyldopa

2.5/25/25

ng/mL

Plasma

HPLC/EC

RR- & SS-Carboxyibuprofen

2.5

μg/mL

Urine

HPLC/FL

Carboxyibuprofen

5

μg/mL

Urine

HPLC/FL

Cefaclor

0.5

μg/mL

Plasma

HPLC/UV

Cefadroxil

0.25

μg/mL

Plasma

HPLC/UV

Cefdinir

25

ng/mL

Plasma

HPLC/UV

Cefixime

50

ng/mL

Plasma

HPLC/UV

Cefprozil

0.25

μg/mL

Plasma

HPLC/UV

Cephalexin

0.25

μg/mL

Plasma

HPLC/UV

Chinin

10

ng/mL

Plasma

HPLC/UV

Chlormezanone

5

ng/mL

Plasma

HPLC/UV

Chlorpropamide

1

μg/mL

Rat Plasma

HPLC/UV

Chlorthalidone

10

ng/mL

Whole Blood

HPLC/UV

Chlorthalidone

0.2

μg/mL

Urine

HPLC/UV

Cimetidine

50

ng/mL

Plasma

HPLC/UV

Cimetidine

25

μg/mL

Urine

HPLC/UV

Cinnarizine

2

ng/mL

Plasma

HPLC/UV

Ciprofloxacin

25

ng/mL

Plasma

HPLC/FL

Ciprofloxacin

2.0

μg/mL

Urine

HPLC/FL

Cisapride

5

ng/mL

Plasma

HPLC/FL

Clavulanic Acid

10

ng/mL

Plasma

HPLC/UV

Clobutinol

1

ng/mL

Plasma

HPLC/UV

Cortisone

5

ng/mL

Plasma

HPLC/UV

Danazole

1

ng/mL

Serum

HPLC/UV

Dazopride

10

ng/mL

Plasma

HPLC/EC

Demeclocycline

100

ng/mL

Plasma

HPLC/UV

Dextromethorphan / 3-hydroxymorphinan / 4-methoxymorphina

n

10

ng/mL

Plasma HPLC/FL

Dextromethorphan / 3-hydroxymorphinan / 4-methoxymorphina

n

0.25

μg/mL

Urine     HPLC/FL

Dextrorphan

10/250

ng/mL

Plasma/Urine

HPLC/FL

Diazepam / Desmethyldiazepam

2

ng/mL

Plasma

HPLC/UV

Diclofenac

10

ng/mL

Plasma

HPLC/UV

Dihydralazine

1

ng/mL

Plasma

HPLC/UV

Dilazep

2.5

ng/mL

Whole Blood

HPLC

Dipyridamole

10

ng/mL

Plasma

HPLC/FL

Disopyramide / N-Desmethyldisopyramide

0.1/0.05

μg/mL

Plasma

HPLC/UV

Domperidone

1.0

ng/mL

Plasma

HPLC/UV

Dothiepin

2

ng/mL

Plasma

HPLC/UV

Dothiepin-S-Oxide

5

ng/mL

Plasma

HPLC/UV

Doxazosin

0.2

ng/mL

Plasma

HPLC/FL

Doxepine / Desmethyldoxepine

0.5

ng/mL

Plasma

HPLC/UV

Doxycycline

50

ng/mL

Plasma

HPLC/UV

Doxylamine

5/100

ng/mL

Plasma/Urine

HPLC/UV

Ebastine

10

ng/mL

Plasma

HPLC/UV

Erythromycin A

0.1

μg/mL

Plasma

HPLC/EC

Etilefrine

10

ng/mL

Plasma

HPLC/UV

Etintidine

100

ng/mL

Plasma

HPLC/UV

Etintidine

10

μg/mL

Urine

HPLC/UV

Etodolac

0.1

μg/mL

Plasma

HPLC/UV

Femoxitine / N-Desmethylfemoxitine

5

ng/mL

Plasma

HPLC/FL

Fenbufen

0.1

μg/mL

Plasma

HPLC/UV

Flavoxate / MFCA metabolite

0.1/50

ng/mL

Plasma

LC/MS/MS/HPLC UV

Fluconazole

50

ng/mL

Plasma

HPLC/UV

Flunitrazepam

0.5

ng/mL

Serum

HPLC/UV

Fluoxetine / Norfluoxetine

1

ng/mL

Plasma

HPLC/UV

Flurazepam / N-Hydroxyethyl & N-Desalkyl metabolites

0.75

ng/mL

Serum

HPLC/UV

Flurbiprofen

0.1

μg/mL

Plasma

HPLC/UV

Flurbiprofen R- / S-

0.5

μg/mL

Urine

HPLC/FL

Flurbiprofen R- / S-

0.25

μg/mL

Plasma

HPLC/FL

Furosemide

10

ng/mL

Plasma

HPLC/FL

Gallopamil

2

ng/mL

Plasma

HPLC/FL

Gemcitabine

40

ng/mL

Plasma/Urine

HPLC/UV

Gemfibrozil

0.5

μg/mL

Plasma

HPLC/UV

Glipizide

10

ng/mL

Plasma

HPLC/UV

Glisoxepide

2.5

ng/mL

Serum

HPLC/UV

Glyburide

5

ng/mL

Plasma

HPLC/UV

Granisetron

100

pg/mL

Plasma

HPLC/Fl

Homogentisic Acid

0.25

μg/mL

Plasma

HPLC/UV

Hydralazine Free & Apparent

2.5/0.5

ng/mL

Plasma/Whole Blood

HPLC/FL

Hydrochlorothiazide

1

ng/mL

Plasma

HPLC/UV

Hydrochlorothiazide

0.05

μg/mL

Urine

HPLC/UV

Hydrocortisone

5

ng/mL

Plasma

HPLC/UV

6−β−Hydroxycortisol

0.1

μg/mL

Urine

HPLC/UV

R- & S-Hydroxyibuprofen

2.5

μg/mL

Urine

HPLC/FL

Hypoxanthine

0.25/0.5

μg/mL

Plasma/Urine

HPLC/UV

Indocyanine Green (ICG)

0.3

μg/mL

Plasma

HPLC/UV

Iodide

0.1

μg/mL

Plasma

HPLC/UV

Isoniazide

0.1

μg/mL

Plasma

HPLC/UV

Ketoconazole

50

ng/mL

Plasma

HPLC/FL

Ketoprofen

5/1000

ng/mL

Plasma/Urine

HPLC/UV

Labetalol

1

ng/mL

Plasma

HPLC/FL

Levetiracetam

0.5

μg/mL

Plasma

HPLC/UV

Levomepromazine

1

ng/mL

Plasma

HPLC/UV

Lornoxicam

25

ng/mL

Plasma

HPLC/UV

Losartan / Losartan Carboxy Acid

10/5

ng/mL

Plasma

HPLC/Fl

Medroxyprogesterone Acetate

4

ng/mL

Serum

HPLC/UV

6-Mercaptopurine

5

ng/mL

Plasma

HPLC/UV

Metamizol

0.3

μg/mL

Plasma

HPLC/UV

Methimazole

10

ng/mL

Plasma

HPLC/EC

Methocarbamol

0.1

μg/mL

Plasma

HPLC/FL

6-Methoxy-2-Naphthaleneacetic Acid

0.1

μg/mL

Plasma

HPLC/FL

5-Methyltetrahydrofolic Acid

10

ng/mL

Plasma

HPLC/UV

Methylsalicylate

80

ng/mL

Plasma

HPLC/FL

Metoclopramide

1

ng/mL

Plasma

HPLC/UV

Metoclopramide

60

ng/mL

Urine

HPLC/FL

Metolazone

2

ng/mL

Plasma

HPLC/Fl

Metoprolol/Hydroxymetoprolol

2.5/1000

ng/mL

Plasma/Urine

HPLC/FL

Mexiletine

10

ng/mL

Plasma

HPLC/UV

Mianserin

1

ng/mL

Plasma

HPLC/UV

Minocycline

25

ng/mL

Plasma

HPLC/UV

Mivazerol

0.1/10

ng/mL

Plasma/Urine

HPLC/FL

Naftidrofuryl

5

ng/mL

Plasma

HPLC/FL

Naloxone

1

ng/mL

Plasma

HPLC/EC

Naltrexone / 6-b-Naltrexol

0.1/0.5

ng/mL

Plasma

HPLC/FL

Naproxen

0.5

μg/mL

Plasma

HPLC/FL

Nefazodone

10

ng/mL

Plasma

HPLC/UV

Nicardipine

0.5

ng/mL

Plasma

HPLC/EC

Nicergoline + M1 and M2 Metabolites

0.5

ng/mL

Plasma

HPLC/UV

Nicorandil

50

ng/mL

Urine

HPLC/UV

Nifedipine / NPO

1

ng/mL

Plasma

HPLC/UV

Nimesulide / Hydroxynimesulide

20

ng/mL

Plasma

HPLC/UV

Nitrofurantoin

5

ng/mL

Plasma

HPLC/UV

Nitrofurantoin

2

μg/mL

Urine

HPLC/UV

Northiaden / Northiaden-S-Oxide

2/5

ng/mL

Plasma

HPLC/UV

Orphenadrine

1

ng/mL

Plasma

HPLC/UV

Oxaprozin

2

μg/mL

Plasma

HPLC/UV

Oxazepam

10

ng/mL

Plasma

HPLC/UV

Oxazepam

0.1

μg/mL

Urine

HPLC/UV

Oxprenolol

2.5

ng/mL

Plasma

HPLC/UV

Papaverine, Phentolamine

1

ng/mL

Plasma

HPLC/UV

Paraxanthine

25

ng/mL

Plasma/Serum

HPLC/UV

Pelargonidin

10/40

ng/mL

Plasma/Urine

HPLC/UV

Pentoxifylline

4

ng/mL

Plasma

HPLC/UV

Phenoxymethylpenicillin (Penicillin V)

0.1

μg/mL

Plasma

HPLC/UV

Phenylpropanolamine

2

ng/mL

Plasma

HPLC/FL

Phenylpropanolamine

5

μg/mL

Urine

HPLC/FL

Phenylpropanolamine D- / L-

8.1

ng/mL

Plasma (Human/Dog)

HPLC/UV

Phenylpropanolamine D- / L-

2.4

ng/mL

Urine (Dog)

HPLC/UV

Phenytoin

0.25

μg/mL

Plasma

HPLC/UV

Free Phenytoin / Phenylhhydantoin / Phenobarbitol

0.1

μg/mL

Urine

HPLC/UV

Phenytoin

1

μg/mL

Urine

HPLC/UV

Pindolol

1

ng/mL

Plasma

HPLC/UV

Piracetam

0.5

μg/mL

Plasma

HPLC/UV

Piroxicam

50

ng/mL

Plasma

HPLC/UV

Prazosin

0.1

ng/mL

Plasma

HPLC/FL

Prednisolone

1

ng/mL

Plasma

HPLC/UV

Prednisone

1

ng/mL

Plasma

HPLC/UV

Prednyliden

5

ng/mL

Plasma

HPLC/UV

Probucol

0.25

μg/mL

Plasma

HPLC/UV

Procainamide / Acetylprocainamide

0.2

μg/mL

Plasma

HPLC/UV

Propofol

2.5

ng/mL

Plasma

HPLC/FL

Propranolol / 4-Hydroxypropranolol

2.5

ng/mL

Plasma

HPLC/FL

Propranolol Glucuronide

1

μg/mL

Urine

HPLC/FL

Pseudoephedrine

0.5

μg/mL

Urine

HPLC/UV

Quinidine

10

ng/mL

Plasma

HPLC/UV

Quinine

10

ng/mL

Plasma

HPLC/UV

Quinolone

50/100

ng/mL

Plasma/Urine

HPLC/UV

Ranitidine

5

ng/mL

Plasma

HPLC/UV

Reserpine

25

pg/mL

Plasma

HPLC/FL

Rifampicin / Desacetylrifampin

0.1

μg/mL

Plasma

HPLC/UV

Rosoxacin

0.1

μg/mL

Plasma/Oviduct/Uterus

HPLC/UV

Salicylic Acid

0.25

μg/mL

Plasma

HPLC/UV

Salicylic Acid

0.7/9.2

μg/mL

Plasma/Urine

HPLC/FL

Salicyluric Acid

25

ng/mL

Plasma

HPLC/UV

Salicyluric Acid

2.5

μg/mL

Urine

HPLC/UV

Sildenafil / N-desmethylsildenafil

1/1

ng/mL

Plasma

HPLC/UV

Sotalol

50

ng/mL

Plasma

HPLC/FL

Sulfamethoxazole

250

ng/mL

Plasma

HPLC/UV

Sulfamethoxazole

1

μg/mL

Urine

HPLC/UV

Sulindac / Sulindacsulfone / Sulindacsulfide

0.25

μg/mL

Plasma

HPLC/UV

Sulpiride

10

ng/mL

Plasma

HPLC/FL

Tamoxifen / N-Desmethyltamoxifen

0.5/0.25

ng/mL

Plasma

HPLC/FL

Telmisartan

500

pg/ml

Plasma

HPLC/Fl

Tenoxicam

20

ng/mL

Plasma

HPLC/UV

Terbutaline

0.25

ng/mL

Plasma

HPLC/EC

Terconazole

0.5

ng/mL

Plasma

HPLC/EC

Terfenadine Metabolite M1

25

ng/mL

Plasma

HPLC/FL

Terfenadine Metabolite M1/M2

250

ng/mL

Urine

HPLC/FL

Tetrazepam

2

ng/mL

Plasma

HPLC/UV

Theophylline

50

ng/mL

Plasma

HPLC/UV

Theophylline

0.2

μg/mL

Serum/Plasma

HPLC/UV

Thiothixene

0.5

ng/mL

Serum

HPLC/UV

Tiaprofenic Acid

100

ng/mL

Plasma

HPLC/UV

Ticlopidine

5

ng/mL

Plasma

HPLC/UV

Timolol

2

ng/mL

Plasma

HPLC/UV

Tolbutamide / Carboxytolbutamide / Hydroxytolbutamide

0.25/0.5/0.5

μg/mL

Plasma

HPLC/UV

Tramadol

2.5

ng/mL

Plasma

HPLC/UV

Triamterene / Hydroxytriamterene Sulfate

5/25

ng/mL

Plasma

HPLC/FL

Triamterene / Hydroxytriamterene Sulfate

0.125/1.25

ng/mL

Urine

HPLC/FL

Trimethoprim/Sulfamethoxazole

10/250

ng/mL

Plasma

HPLC/UV

Trimethoprim

1

μg/mL

Urine

HPLC/UV

Trimipramine / N-desmethyltrimipramine

2 / 2

ng/mL

Plasma

HPLC/UV

Valsartan

50

ng/mL

Plasma

HPLC/Fl

Verapamil / Norverapamil

2.5

ng/mL

Plasma

HPLC/FL

Veratric Acid

50

ng/mL

Plasma

HPLC/UV

Vitamin E

0.5

μg/mL

Plasma

HPLC/UV

Warfarin R- & S-

50

ng/mL

Plasma

HPLC/FL

Xanthine

0.5/1.0

μg/mL

Plasma/Urine

HPLC/UV

Zatebradine

1.5

ng/mL

Plasma

HPLC/FL

Zonisamide

50

ng/mL

Serum

HPLC/UV